Apparently one scientific study demonstrated that vitamin C did show some efficacy in curing bacterial vaginosis, a vaginal infection as a result of friendly bacteria (the Lactobacillus species) being replaced by an excessive population of bad bacteria (the aerobic and anaerobic bacteria).

If that's the case, women who suffered from bacterial vaginosis has now another natural remedy for bacterial vaginosis to account on.

Bacterial vaginosis natural treatment with vitamin C


Below is an abstract of the study's methods and results.

Researchers: Petersen EE, Genet M, Caserini M, Palmieri R.
Published in: Arzneimittelforschung. 2011;61(4):260-5.
Title: Efficacy of vitamin C vaginal tablets in the treatment of bacterial vaginosis

A randomised, double blind, parallel groups, placebo controlled clinical trial was conducted to assess the efficacy and safety profile of 250 mg ascorbic acid (Vit. C, Vagi C) in women with bacterial vaginosis (BV).

Overall, 277 out-patients with at least three of the following signs (white discharge that smoothly coats the vaginal walls, pH of vaginal fluid > 4.5, a fishy odor of vaginal discharge before or after addition of 10% KOH and presence of clue cells on microscopic examination) were randomised to apply a tablet deeply into the vagina once daily for 6 days.

The primary efficacy endpoint was the cure rate, defined as the recovery of all inclusion criteria. In the intent-to-treat (ITT) population, cure was achieved by 55.3% of patients with Vit. C (n=141) and by 25.7% of patients with placebo (n=136). The between-group difference was 29.6% (p<0.001).

In the per-protocol (PP) population, cure rate was 66.4% with Vit. C (n=116) and 27.1% with placebo (n = 118), respectively. Between-group difference was 39.3% (p<0.001).

In a subset of patients with centralised evaluation of the vaginal swab, cure in ITT was achieved by 86.3% of patients with Vit. C (n=51) and by 7.6% of patients with placebo (n=53), the between-group difference was 78.7% (p<0.0001). Cure rate in PP was 86.0% with Vit. C (n=50) and 6.1% with placebo (n=49), between-group difference was 79.9% (p<0.0001).

Both Vit. C and placebo were well tolerated and no differences in safety profile were evident between groups. The results support an effective and safe use of silicon-coated Vit. C vaginal tablets in the management of BV.

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